• Active Ingredients: Sitagliptin 50 mg, Metformin 1000 mg.
• Form: Film-coated tablets (56 per pack).
• Indications:
  • Treatment of type 2 diabetes in adults.
  • Patients not adequately controlled on metformin alone or already being treated with sitagliptin and metformin separately.

 

When Should Janumet NOT Be Used?

Do NOT use Janumet if you:

• Have type 1 diabetes or diabetic ketoacidosis.
• Are allergic to sitagliptin, metformin, or any of the excipients in the product.
• Suffer from severe kidney problems or are undergoing dialysis.
• Have acute or chronic metabolic acidosis, including lactic acidosis.
• Consume excessive alcohol, as it increases the risk of lactic acidosis.
• Are experiencing severe dehydration or shock conditions.

 

When Should Janumet Be Used With Caution?

Consult your doctor before using Janumet if you:

• Have a history of pancreatitis.
• Suffer from liver problems or frequent infections.
• Are undergoing imaging procedures involving iodine-based contrast agents, as these can increase the risk of lactic acidosis.
• Are over 65 years old, due to potential kidney function decline.
• Are pregnant, planning to become pregnant, or breastfeeding.
• Engage in strenuous exercise or have conditions that can lead to dehydration.

 

When Should You Stop Using Janumet and Seek Immediate Medical Attention?

Stop taking Janumet and contact your healthcare provider or visit the nearest hospital if you experience:

Signs of Lactic Acidosis:

• Severe nausea, vomiting, or stomach pain.
• Muscle pain, unusual fatigue, or difficulty breathing.
• Dizziness or feeling unusually cold (especially in hands and feet).

Symptoms of Pancreatitis:

• Persistent, severe abdominal pain that radiates to your back.
• Nausea or vomiting not related to food intake.

Allergic Reactions:

• Swelling of the face, lips, tongue, or throat.
• Difficulty breathing or a severe skin rash.

Unexplained Blood Sugar Changes:

• Hypoglycemia symptoms: Sweating, tremors, confusion, or fainting.
• Hyperglycemia symptoms: Extreme thirst, frequent urination, and blurred vision.

 

Drug Interactions:

Janumet may interact with certain substances, so inform your healthcare provider if you are using:

• Alcohol: Can increase the risk of lactic acidosis and hypoglycemia.
• Iodine contrast agents: May increase the risk of kidney dysfunction; temporary discontinuation of Janumet may be required.
• Steroids or diuretics: May affect blood sugar levels.
• Beta-blockers: Can mask symptoms of hypoglycemia.
• Other antidiabetic medications: May increase the risk of low blood sugar.

 

Technical Specifications:

• Dosage Form: Oral tablet, to be taken with meals to reduce gastrointestinal side effects.
• Storage: Store at room temperature (15–30°C) in a dry place, away from direct sunlight.
• Administration:
  • Swallow the tablet whole; do not crush or chew.
  • Recommended dosage should be determined by your healthcare provider.

Contact Us:

If you have any questions or concerns about Janumet, please don’t hesitate to contact us. We’re here to help:
Email: info@staminapharma.com